Therapeutic Plasma Exchange (TPE) Treatment

What Is Therapeutic Plasma Exchange?

Therapeutic Plasma Exchange (TPE) is a well-established medical procedure that separates your blood plasma from its cellular components, removes the portion containing accumulated toxins, metabolic waste, and inflammatory proteins, and replaces it with a purified albumin solution. The refreshed blood is then returned to your body.

Think of it as a deep reset for your circulatory system. Over time, plasma may accumulate substances that are associated with chronic inflammation, immune dysfunction, and diminished cellular performance. TPE is designed to help your body clear what it no longer needs, making room for renewed balance and vitality.

CLEARER MIND

Mental Clarity

Many people describe a “fog lift” feeling —sharper focus, cleaner thinking, faster recall.

Lighter Body

Less Heavy

A noticeable sense of lightness — like your system is running with less drag.

More Energy

Cleaner Energy

Not “wired.” More steady, usable energy throughout the day.

Calmer Baseline

Nervous System Reset

Many report feeling calmer, more emotionally even, and less reactive.

How the Procedure Works

1

Consultation and Assessment

Your provider reviews your health history, vitals, medications, and hydration status to confirm you're a good candidate for the procedure.

3

Plasma Replacement

A portion of your plasma is removed and replaced with albumin protein — a purified solution that helps replenish essential nutrients and restore balance.

2

Blood Draw and Filtration

Blood is drawn and circulated through a high-precision, FDA-cleared filtration device that separates plasma from blood cells.

4

Return and Recovery

Refreshed blood is returned to your body. Post-treatment, we recommend 24 hours of rest, hydration, and avoiding strenuous activity.

What TPE May Support

Toxin and Waste Reduction

TPE is designed to help reduce the circulation of toxins, metabolic waste, and inflammatory proteins that may accumulate in the bloodstream over time.

Immune System Balance

By helping to remove harmful antibodies, TPE may support a more balanced immune response - particularly for individuals managing autoimmune-related symptoms.

Mental Clarity

Many individuals who undergo TPE report improvements in cognitive function and reduced brain fog, which may be associated with lower inflammatory burden.

Cellular-Level Support

TPE may support healthy aging at the cellular level by helping the body start from a cleaner, less burdened internal environment.

Understanding
If You're a Candidate

May Be Appropriate For

Healthy individuals seeking proactive health optimization
Those managing chronic inflammation
Individuals with autoimmune-related symptoms
People experiencing persistent brain fog or low energy
Those interested in supporting their body's natural detoxification processes

Not Appropriate For

Those with active infections
Individuals with severe anemia or coagulation disorders
Those with advanced heart disease
Individuals with uncontrolled autoimmune disorders
Those with poor venous access

Every individual is different. A consultation with your Humanaut Health provider is the best way to determine whether TPE may be a fit for your health goals.

Expert Perspective

"For individuals seeking to optimize general health, improve autoimmune symptoms, or support detoxification at a cellular level, TPE is a transformative therapy. It represents the kind of advanced, evidence-based approach that defines what we do at Humanaut Health."

Amy Killen, MD

Chief Medical Officer, Humanaut Health

Why Humanaut Health

A Different
Standard of Care

Clinical Safety

Every TPE session is delivered by registered clinicians in a private setting under direct medical provider supervision. Your safety is never a secondary consideration.

Comprehensive Health Management

TPE at Humanaut Health isn’t an isolated service. Your providers manage this therapy alongside your broader health optimization plan - connecting the dots between diagnostics, therapies, and measurable outcomes.

Comfortable,
Private Environment

Treatments take place in private clinical rooms designed for comfort. No crowded infusion centers. Just you and your care team.

Leading Medical Technology Partners

We work with global medical technology leaders to ensure every device and protocol meets the highest standards of precision and safety.

Frequently asked questions

/01/ What exactly is Therapeutic Plasma Exchange?

TPE is a medical procedure that filters your blood, removes a portion of plasma containing toxins, inflammatory proteins, and metabolic waste, and replaces it with a purified albumin solution. The refreshed blood is then returned to your body.

/02/ Is Therapeutic Plasma Exchange safe?

TPE is a well-established medical therapy. At Humanaut Health, it is performed by registered nurses using FDA-cleared equipment under direct medical provider supervision. As with any medical procedure, there are potential risks, which your provider will discuss with you during your consultation.

/03/ Does the procedure hurt?

Most individuals experience little to no pain. You may feel slight discomfort during needle insertion or a mild sensation of coldness from the replacement fluids. Your nurse monitors you closely throughout for comfort.

/04/ How many sessions will I need?

The number of sessions depends on your individual health goals and condition. Some people may benefit from one to six sessions, with quarterly maintenance recommended afterward. Your provider will create a personalized plan during your consultation.

/05/ How much does stem cell therapy cost?

Stem cell therapy typically starts at $4,500. For skin and scalp treatments, the cost may be slightly less.

/06/ How long does each session take?

A typical TPE session takes between two and four hours. Plan for a relaxed experience — many clients read, rest, or watch content during their session.

/07/ What’s the difference between TPE and EBO2 Therapy?

While both therapies involve blood, they work differently. TPE focuses on the removal of toxins, waste, and harmful antibodies from plasma, supporting immune, energy, and cognitive health. EBO2 focuses on enhanced oxygen delivery to help reduce inflammation. Your provider can help you determine which therapy - or combination - may be best for your goals.

/08/ What should I expect after treatment?

We recommend 24 hours of rest, staying well hydrated, and avoiding strenuous activity. Many individuals report feeling renewed within a few days following the procedure.

/09/ What services pair well with TPE?

Many Humanaut Health clients complement TPE with NAD+ infusions and ongoing care through our Premium Care Membership. Your provider can recommend the right combination for your goals.

Ready to Explore
What TPE Can Do for You?

Schedule a consultation with a Humanaut Health provider to learn whether Therapeutic Plasma Exchange may be the right fit for your health journey.

An Oil Change for Your Body

Frequently asked questions